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KARS 抗体 (AA 101-400)

This anti-KARS antibody is a 兔 多克隆 antibody detecting KARS in WB, IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7158683
发货至: 中国

Quick Overview for KARS 抗体 (AA 101-400) (ABIN7158683)

抗原

See all KARS 抗体
KARS (Lysyl-tRNA Synthetase (KARS))

适用

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宿主

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克隆类型

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多克隆

标记

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This KARS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 101-400

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Lysine--tRNA ligase protein (101-400AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KARS (Lysyl-tRNA Synthetase (KARS))

    别名

    KARS

    背景

    Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). (Microbial infection) Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.

    Aliases: CMTRIB antibody, DFNB89 antibody, EC 6.1.1.6 antibody, KARS 1 antibody, KARS 2 antibody, KARS antibody, KARS1 antibody, KARS2 antibody, KIAA0070 antibody, KRS antibody, Lysine tRNA ligase antibody, Lysine--tRNA ligase antibody, LysRS antibody, Lysyl tRNA synthetase antibody, Lysyl-tRNA synthetase antibody, SYK_HUMAN antibody

    UniProt

    Q15046
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