LGR6 抗体 (AA 839-962) (FITC)
Quick Overview for LGR6 抗体 (AA 839-962) (FITC) (ABIN7158136)
抗原
See all LGR6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 839-962
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)
-
亚型
- IgG
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
-
别名
- LGR6
-
背景
-
Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Aliases: FLJ14471 antibody, Gonadotropin receptor antibody, GPCR antibody, Leucine rich repeat containing G protein coupled receptor 6 antibody, Leucine-rich repeat-containing G-protein coupled receptor 6 antibody, Lgr6 antibody, LGR6_HUMAN antibody, VTS20631 antibody
-
UniProt
- Q9HBX8
抗原
-