L3MBTL1 抗体 (AA 513-752)
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Quick Overview for L3MBTL1 抗体 (AA 513-752) (ABIN7158005)
抗原
See all L3MBTL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 513-752
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原理
- L3MBTL1 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Lethal(3)malignant brain tumor-like protein 1 protein (513-752AA)
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亚型
- IgG
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anti-L(3)mbt-Like 1 (L3MBTL1) (Center) antibody
L3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 1-772) antibodyL3MBTL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 82-298) antibodyL3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 451-485) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (N-Term) antibodyL3MBTL1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 144-193) antibodyL3MBTL1 适用: 人, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 221-270) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 442-491) antibodyL3MBTL1 适用: 人, 小鼠, 犬, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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别名
- L3MBTL1
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背景
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Background: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a \\\'reader\\\' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at \\\'Lys-26\\\' (H1bK26me1 and H1bK26me2) and histone H4 at \\\'Lys-20\\\' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at \\\'Lys-860\\\'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis.
Aliases: dJ138B7.3 antibody, H-L(3)MBT antibody, H-l(3)mbt protein antibody, KIAA0681 antibody, L(3)mbt protein homolog antibody, L(3)mbt-like antibody, L3MBT antibody, L3MBTL antibody, L3MBTL1 antibody, Lethal (3) malignant brain tumor l(3 antibody, Lethal(3)malignant brain tumor-like protein 1 antibody, LMBL1_HUMAN antibody, RGD1307316 antibody, ZC2HC3 antibody
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UniProt
- Q9Y468
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途径
- Chromatin Binding
抗原
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