LGMN 抗体 (AA 199-312) (HRP)
Quick Overview for LGMN 抗体 (AA 199-312) (HRP) (ABIN7157974)
抗原
See all LGMN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 199-312
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Legumain protein (199-312AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LGMN (Legumain (LGMN))
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别名
- LGMN
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背景
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Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Aliases: AEP antibody, Asparaginyl endopeptidase antibody, cysteine 1 antibody, Cysteine protease 1 antibody, EC 3.4.22.34 antibody, Legumain antibody, LGMN antibody, LGMN_HUMAN antibody, LGMN1 antibody, Protease antibody, Protease cysteine 1 (legumain) antibody, Protease cysteine 1 antibody, PRSC1 antibody
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UniProt
- Q99538
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途径
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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