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KLF1 抗体 (AA 1-362) (HRP)

This anti-KLF1 antibody is a 兔 多克隆 antibody detecting KLF1 in ELISA. Suitable for 人.
产品编号 ABIN7157706
发货至: 中国

Quick Overview for KLF1 抗体 (AA 1-362) (HRP) (ABIN7157706)

抗原

See all KLF1 抗体
KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

适用

  • 42
  • 6
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  • 2

宿主

  • 32
  • 12
  • 1

克隆类型

  • 34
  • 12
多克隆

标记

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This KLF1 antibody is conjugated to HRP

应用范围

  • 30
  • 23
  • 6
  • 4
  • 2
  • 2
  • 2
ELISA
  • 抗原表位

    • 9
    • 5
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1-362

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Krueppel-like factor 1 protein (1-362AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

    别名

    KLF1

    背景

    Background: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.

    Aliases: CDAN4 antibody, EKLF antibody, EKLF PEN antibody, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody, Erythroid krueppel-like transcription factor antibody, Erythroid Kruppel like factor antibody, Erythroid specific transcription factor EKLF antibody, HBFQTL6 antibody, Human erythroid-specific transcription factor EKLF mRNA complete cds antibody, INLU antibody, Klf1 antibody, KLF1_HUMAN antibody, Krueppel-like factor 1 antibody, Kruppel like factor 1 (erythroid) antibody

    UniProt

    Q13351
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