KIDINS220 抗体 (AA 1077-1370) (Biotin)
Quick Overview for KIDINS220 抗体 (AA 1077-1370) (Biotin) (ABIN7157551)
抗原
See all KIDINS220 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1077-1370
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原理
- KIDINS220 Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA)
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亚型
- IgG
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anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1077-1370) antibody
KIDINS220 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (Internal Region) antibodyKIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (C-Term) antibodyKIDINS220 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (pSer918) antibodyKIDINS220 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1335-1348), (Intracellular) antibodyKIDINS220 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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别名
- KIDINS220
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背景
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Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
Aliases: Ankyrin repeat-rich membrane-spanning protein antibody, arms antibody, KDIS_HUMAN antibody, kidins220 antibody, Kinase D interacting substance of 220 kDa antibody, Kinase D-interacting substrate of 220 kDa antibody, rgd 619949 antibody
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UniProt
- Q9ULH0
抗原
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