KLHL22 抗体 (AA 2-300)
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北京 101111
Quick Overview for KLHL22 抗体 (AA 2-300) (ABIN7157281)
抗原
See all KLHL22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-300
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原理
- KLHL22 Antibody
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交叉反应
- 小鼠
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Kelch-like protein 22 protein (2-300AA)
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亚型
- IgG
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anti-Kelch-Like 22 (KLHL22) antibody
KLHL22 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7B10 unconjugated
anti-Kelch-Like 22 (KLHL22) (AA 175-224) antibodyKLHL22 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 22 (KLHL22) (N-Term) antibodyKLHL22 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 22 (KLHL22) (AA 586-614), (C-Term) antibodyKLHL22 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB25550 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KLHL22 (Kelch-Like 22 (KLHL22))
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别名
- KLHL22
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背景
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Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Aliases: KLHL22Kelch-like protein 22 antibody
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UniProt
- Q53GT1
抗原
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