KLHL12 抗体 (AA 1-220) (Biotin)
Quick Overview for KLHL12 抗体 (AA 1-220) (Biotin) (ABIN7157268)
抗原
See all KLHL12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Kelch-like protein 12 protein (1-220AA)
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亚型
- IgG
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anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 1-220) antibody
KLHL12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) antibodyKLHL12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) antibodyKLHL12 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 81-341) antibodyKLHL12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) antibodyKLHL12 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 376-404), (C-Term) antibodyKLHL12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37184 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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别名
- KLHL12
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背景
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Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
Aliases: C3IP1 antibody, CUL3 interacting protein 1 antibody, CUL3-interacting protein 1 antibody, DKIR antibody, DKIR homolog antibody, FLJ27152 antibody, hDKIR antibody, Kelch like 12 (Drosophila) antibody, Kelch like 12 antibody, Kelch like 12 variant antibody, Kelch like protein 12 antibody, Kelch like protein C3IP1 antibody, kelch-like family member 12 antibody, Kelch-like protein 12 antibody, KLH12_HUMAN antibody, KLHL 12 antibody, klhl12 antibody, OTTHUMP00000038799 antibody
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UniProt
- Q53G59
抗原
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