IST1 抗体 (AA 172-284) (Biotin)
Quick Overview for IST1 抗体 (AA 172-284) (Biotin) (ABIN7157139)
抗原
See all IST1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 172-284
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human IST1 homolog protein (172-284AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
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别名
- IST1
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背景
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Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).
Aliases: hIST1 antibody, Increased sodium tolerance 1 antibody, Increased sodium tolerance 1 homolog antibody, IST1 homolog antibody, IST1_HUMAN antibody, KIAA0174 antibody, MAPK activating protein PM28 antibody, MGC117220 antibody, MGC128433 antibody, Putative MAPK-activating protein PM28 antibody
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UniProt
- P53990
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途径
- Regulation of Cell Size
抗原
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