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ISCU 抗体 (AA 1-167)

This anti-ISCU antibody is a 兔 多克隆 antibody detecting ISCU in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7157058
发货至: 中国

Quick Overview for ISCU 抗体 (AA 1-167) (ABIN7157058)

抗原

See all ISCU 抗体
ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

适用

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宿主

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克隆类型

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多克隆

标记

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This ISCU antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-167

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein (1-167AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

    别名

    ISCU

    背景

    Background: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:11060020). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU. In a second step, the cluster is released from ISCU, transferred to a glutaredoxin GLRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-LYRM4/ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).

    Aliases: 2310020H20Rik antibody, HML antibody, hnifU antibody, Iron sulfur cluster assembly enzyme ISCU mitochondrial antibody, Iron sulfur cluster scaffold homolog (E. coli) antibody, Iron sulfur cluster scaffold homolog antibody, Iron-sulfur cluster assembly enzyme ISCU antibody, Iscu antibody, IscU iron sulfur cluster scaffold homolog antibody, ISCU_HUMAN antibody, ISU2 antibody, MGC74517 antibody, mitochondrial antibody, NIFU antibody, NifU like N terminal domain containing antibody, NifU like N terminal domain containing protein antibody, NifU like protein antibody, NifU-like N-terminal domain-containing protein antibody, NifU-like protein antibody, NIFUN antibody, Nitrogen fixation cluster like antibody, OTTHUMP00000238760 antibody, OTTHUMP00000238761 antibody, OTTHUMP00000238762 antibody, OTTHUMP00000238764 antibody, OTTHUMP00000238765 antibody

    UniProt

    Q9H1K1
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