电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ISCU 抗体 (AA 1-167)

The 兔 多克隆 anti-ISCU antibody is suitable to detect ISCU in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN7157058
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ISCU 抗体 (AA 1-167) (ABIN7157058)

抗原

See all ISCU 抗体
ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

适用

  • 27
  • 14
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 23
  • 4

克隆类型

  • 23
  • 3
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
This ISCU antibody is un-conjugated

应用范围

  • 22
  • 16
  • 4
  • 4
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-167

    原理

    ISCU Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein (1-167AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

    别名

    ISCU

    背景

    Background: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:11060020). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU. In a second step, the cluster is released from ISCU, transferred to a glutaredoxin GLRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-LYRM4/ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).

    Aliases: 2310020H20Rik antibody, HML antibody, hnifU antibody, Iron sulfur cluster assembly enzyme ISCU mitochondrial antibody, Iron sulfur cluster scaffold homolog (E. coli) antibody, Iron sulfur cluster scaffold homolog antibody, Iron-sulfur cluster assembly enzyme ISCU antibody, Iscu antibody, IscU iron sulfur cluster scaffold homolog antibody, ISCU_HUMAN antibody, ISU2 antibody, MGC74517 antibody, mitochondrial antibody, NIFU antibody, NifU like N terminal domain containing antibody, NifU like N terminal domain containing protein antibody, NifU like protein antibody, NifU-like N-terminal domain-containing protein antibody, NifU-like protein antibody, NIFUN antibody, Nitrogen fixation cluster like antibody, OTTHUMP00000238760 antibody, OTTHUMP00000238761 antibody, OTTHUMP00000238762 antibody, OTTHUMP00000238764 antibody, OTTHUMP00000238765 antibody

    UniProt

    Q9H1K1
You are here: