Inversin 抗体 (AA 1-101)
Quick Overview for Inversin 抗体 (AA 1-101) (ABIN7157008)
抗原
See all Inversin (INVS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-101
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Inversin protein (1-101AA)
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亚型
- IgG
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anti-Inversin (INVS) (AA 1-237) antibody
INVS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-91) antibodyINVS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-90) antibodyINVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Inversin (INVS)
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别名
- INVS
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背景
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Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).
Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody
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UniProt
- Q9Y283
抗原
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