EBI3 抗体 (AA 21-227)
Quick Overview for EBI3 抗体 (AA 21-227) (ABIN7156880)
抗原
See all EBI3 (IL-27b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-227
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Interleukin-27 subunit beta protein (21-227AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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别名
- EBI3
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背景
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Background: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Aliases: cytokine receptor antibody, EBI3 antibody, EBV induced gene 3 protein antibody, EBV-induced gene 3 protein antibody, Epstein Barr virus induced 3 antibody, Epstein Barr virus induced gene 3 antibody, Epstein Barr virus induced gene 3 protein antibody, Epstein-Barr virus-induced gene 3 protein antibody, IL 27 subunit beta antibody, IL 27B antibody, IL-27 subunit beta antibody, IL-27B antibody, IL27 subunit antibody, IL27 subunit beta antibody, IL27B antibody, IL27B_HUMAN antibody, IL35 subunit antibody, interleukin 27 subunit beta antibody, Interleukin-27 subunit beta antibody
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UniProt
- Q14213
抗原
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