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IL12B 抗体 (AA 23-328)

This anti-IL12B antibody is a 兔 多克隆 antibody detecting IL12B in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7156785
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for IL12B 抗体 (AA 23-328) (ABIN7156785)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 23-328

    原理

    IL12B Antibody

    交叉反应

    小鼠

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Interleukin-12 subunit beta protein (23-328AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL12B

    背景

    Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Ref.12Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

    Aliases: CLMF antibody, CLMF p40 antibody, CLMF2 antibody, Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody, IL 12B antibody, IL-12 subunit p40 antibody, IL-12B antibody, IL12 p40 antibody, IL12B antibody, IL12B_HUMAN antibody, IMD28 antibody, IMD29 antibody, Interleukin 12 beta chain antibody, Interleukin 12 p40 antibody, Interleukin-12 subunit beta antibody, NK cell stimulatory factor chain 2 antibody, NKSF antibody, NKSF2 antibody

    UniProt

    P29460

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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