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AIM2 抗体 (AA 81-326) (FITC)

This FITC-conjugated 兔 多克隆 anti-AIM2 antibody specifically detects AIM2 in not_set. The antibody is reactive with 人 samples.
产品编号 ABIN7156705
发货至: 中国
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Quick Overview for AIM2 抗体 (AA 81-326) (FITC) (ABIN7156705)

抗原

See all AIM2 抗体
AIM2 (Absent in Melanoma 2 (AIM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This AIM2 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 81-326

    原理

    AIM2 Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Interferon-inducible protein AIM2 protein (81-326AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    AIM2 (Absent in Melanoma 2 (AIM2))

    别名

    AIM2

    背景

    Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

    Aliases: Absent in melanoma 2 antibody, AIM 2 antibody, Aim2 antibody, AIM2_HUMAN antibody, Interferon-inducible protein AIM2 antibody, OTTHUMP00000035296 antibody, PYHIN4 antibody

    UniProt

    O14862

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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