IFIT2 抗体 (AA 130-265)
Quick Overview for IFIT2 抗体 (AA 130-265) (ABIN7156667)
抗原
See all IFIT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-265
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交叉反应
- 人, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
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别名
- IFIT2
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背景
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Background: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2\\\'-O-methylation of the 5\\\' cap. The ribose 2\\\'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5\\\' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
Aliases: CIG-42 antibody, cig42 antibody, G10P2 antibody, GARG 39 antibody, Glucocorticoid attenuated response gene 39 antibody, IFI 54 antibody, IFI 54K antibody, IFI-54K antibody, IFI54 antibody, IFIT 2 antibody, IFIT-2 antibody, IFIT2 antibody, IFIT2_HUMAN antibody, Interferon induced 54 kDa protein antibody, Interferon induced protein 54 antibody, Interferon induced protein with tetratricopeptide repeats 2 antibody, Interferon, alpha inducible protein (MW 54kD) antibody, Interferon-induced 54 kDa protein antibody, Interferon-induced protein with tetratricopeptide repeats 2 antibody, ISG 54 K antibody, ISG 54K antibody, ISG-54 K antibody, ISG54 antibody
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UniProt
- P09913
抗原
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