IFIT1 抗体 (AA 1-181)
Quick Overview for IFIT1 抗体 (AA 1-181) (ABIN7156663)
抗原
See all IFIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-181
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Interferon-induced protein with tetratricopeptide repeats 1 protein (1-181AA)
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亚型
- IgG
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibody
IFIT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) antibodyIFIT1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (Internal Region) antibodyIFIT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibodyIFIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) (AA 1-478) antibodyIFIT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
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别名
- IFIT1
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背景
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Background: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5\\\'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2\\\'-O-methylation of the 5\\\' cap and bear a 5\\\'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Aliases: C56 antibody, G10P1 antibody, GARG 16 antibody, GARG16 antibody, IFI 56 antibody, IFI 56K antibody, IFI-56K antibody, IFI56 antibody, IFIT-1 antibody, Ifit1 antibody, IFIT1_HUMAN antibody, IFNAI1 antibody, Interferon alpha inducible protein (MW 56kD) antibody, Interferon induced 56 kDa protein antibody, Interferon induced protein 56 antibody, Interferon inducible mRNA 561 antibody, Interferon-induced 56 kDa protein antibody, Interferon-induced protein with tetratricopeptide repeats 1 antibody, ISG56 antibody, OTTHUMP00000020062 antibody, P56 antibody, RNM561 antibody
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UniProt
- P09914
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途径
- Hepatitis C
抗原
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