IFIH1 抗体 (AA 700-1025)
Quick Overview for IFIH1 抗体 (AA 700-1025) (ABIN7156651)
抗原
See all IFIH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-1025
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Interferon-induced helicase C domain-containing protein 1 protein (700-1025AA)
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亚型
- IgG
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anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-205) antibody
IFIH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (N-Term) antibodyVerified IFIH1 适用: 人, 猴 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 612-661) antibodyIFIH1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-221) antibodyIFIH1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 928-1023) antibodyIFIH1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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别名
- IFIH1
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背景
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Background: Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking 2\'-O-methylation at their 5\' cap and long-dsRNA (>1 kb in length). Upon ligand binding it associates with mitochondria antiviral signaling protein (MAVS/IPS1) which activates the IKK-related kinases: TBK1 and IKBKE which phosphorylate interferon regulatory factors: IRF3 and IRF7 which in turn activate transcription of antiviral immunological genes, including interferons (IFNs), IFN-alpha and IFN-beta. Responsible for detecting the Picornaviridae family members such as encephalomyocarditis virus (EMCV) and mengo encephalomyocarditis virus (ENMG). Can also detect other viruses such as dengue virus (DENV), west Nile virus (WNV), and reovirus. Also involved in antiviral signaling in response to viruses containing a dsDNA genome, such as vaccinia virus. Plays an important role in amplifying innate immune signaling through recognition of RNA metabolites that are produced during virus infection by ribonuclease L (RNase L). May play an important role in enhancing natural killer cell function and may be involved in growth inhibition and apoptosis in several tumor cell lines.
Aliases: CADM-140 autoantigen antibody, Clinically amyopathic dermatomyositis autoantigen 140 kDa antibody, DEAD/H (Asp Glu Ala Asp/His) box polypeptide antibody, DEAD/H box polypeptide antibody, Helicard antibody, Helicase with 2 CARD domains antibody, Hlcd antibody, IDDM 19 antibody, IDDM19 antibody, IFIH 1 antibody, Ifih1 antibody, IFIH1_HUMAN antibody, Interferon induced helicase C domain containing protein 1 antibody, interferon induced with helicase C domain 1 antibody, Interferon induced with helicase C domain protein 1 antibody, Interferon-induced helicase C domain-containing protein 1 antibody, Interferon-induced with helicase C domain protein 1 antibody, MDA 5 antibody, MDA-5 antibody, Melanoma differentiation associated protein 5 antibody, Melanoma differentiation-associated gene 5 antibody, Melanoma differentiation-associated protein 5 antibody, MGC133047 antibody, Murabutide down regulated protein antibody, Murabutide down-regulated protein antibody, RH 116 antibody, RH116 antibody, RIG I like receptor 2 antibody, RLR 2 antibody, RNA helicase DEAD box protein 116 antibody, RNA helicase-DEAD box protein 116 antibody
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UniProt
- Q9BYX4
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途径
- Activation of Innate immune Response
抗原
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