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IRF8 抗体 (AA 137-426)

This 兔 多克隆 anti-IRF8 antibody specifically detects IRF8 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7156635
发货至: 中国
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Quick Overview for IRF8 抗体 (AA 137-426) (ABIN7156635)

抗原

See all IRF8 抗体
IRF8 (Interferon Regulatory Factor 8 (IRF8))

适用

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宿主

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克隆类型

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多克隆

标记

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This IRF8 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 137-426

    原理

    IRF8 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Interferon regulatory factor 8 protein (137-426AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IRF8 (Interferon Regulatory Factor 8 (IRF8))

    别名

    IRF8

    背景

    Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.

    Aliases: H ICSBP antibody, H-ICSBP antibody, HGNC:5358 antibody, HICSBP antibody, ICSBP 1 antibody, ICSBP antibody, ICSBP1 antibody, Interferon consensus sequence binding protein 1 antibody, Interferon consensus sequence binding protein antibody, Interferon consensus sequence-binding protein antibody, Interferon regulatory factor 8 antibody, IRF 8 antibody, IRF-8 antibody, Irf8 antibody, IRF8_HUMAN antibody, MYLS antibody

    UniProt

    Q02556

    途径

    Cellular Response to Molecule of Bacterial Origin
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