Integrin Alpha2b 抗体 (AA 639-887)
Quick Overview for Integrin Alpha2b 抗体 (AA 639-887) (ABIN7156456)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 639-887
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Integrin alpha-IIb protein (639-887AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Integrin Alpha2b (CD41)
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别名
- ITGA2B
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背景
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Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Aliases: antigen CD41 antibody, BDPLT16 antibody, BDPLT2 antibody, CD41 antibody, CD41B antibody, form 2 antibody, GP2B antibody, GPalpha IIb antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, Integrin alpha 2b antibody, Integrin alpha IIb antibody, Integrin alpha-IIb light chain antibody, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody, ITA2B_HUMAN antibody, Itga2b antibody, ITGAB antibody, platelet fibrinogen receptor, alpha subunit antibody, platelet glycoprotein IIb of IIb/IIIa complex antibody, Platelet membrane glycoprotein IIb antibody, platelet specific antigen BAK antibody, PPP1R93 antibody
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UniProt
- P08514
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途径
- Integrin Complex
抗原
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