IGF2BP3 抗体 (AA 1-100)
Quick Overview for IGF2BP3 抗体 (AA 1-100) (ABIN7156360)
抗原
See all IGF2BP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
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别名
- IGF2BP3
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背景
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Background: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \\\'caging\\\' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\\\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\\\'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.
Aliases: Cancer/testis antigen 98 antibody, CT98 antibody, DKFZp686F1078 antibody, hKOC antibody, IF2B3_HUMAN antibody, IGF II mRNA binding protein 3 antibody, IGF-II mRNA-binding protein 3 antibody, IGF2 mRNA binding protein 3 antibody, IGF2 mRNA-binding protein 3 antibody, IGF2BP3 antibody, IMP 3 antibody, IMP-3 antibody, Insulin like growth factor 2 mRNA binding protein 3 antibody, Insulin-like growth factor 2 mRNA-binding protein 3 antibody, KH domain containing protein overexpressed in cancer antibody, KH domain-containing protein overexpressed in cancer antibody, KOC 1 antibody, KOC1 antibody, VICKZ 3 antibody, VICKZ family member 3 antibody, VICKZ3 antibody
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UniProt
- O00425
抗原
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