ING3 抗体 (AA 51-223)
Quick Overview for ING3 抗体 (AA 51-223) (ABIN7156249)
抗原
See all ING3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-223
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Inhibitor of growth protein 3 protein (51-223AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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别名
- ING3
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背景
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Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Aliases: ING3 antibody, HSPC301 antibody, Inhibitor of growth protein 3 antibody, p47ING3 antibody
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UniProt
- Q9NXR8
抗原
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