Importin 11 抗体 (AA 1-270) (HRP)
Quick Overview for Importin 11 抗体 (AA 1-270) (HRP) (ABIN7156141)
抗原
See all Importin 11 (IPO11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Importin-11 protein (1-270AA)
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亚型
- IgG
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anti-Importin 11 (IPO11) antibody
IPO11 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 56-85), (N-Term) antibodyIPO11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23487 unconjugated
anti-Importin 11 (IPO11) antibodyIPO11 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 1-50) antibodyIPO11 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 328-377) antibodyIPO11 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 776-975) antibodyIPO11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Importin 11 (IPO11)
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别名
- IPO11
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背景
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Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
Aliases: Imp11 antibody, Importin 11 antibody, Importin-11 antibody, IPO11 antibody, IPO11_HUMAN antibody, Ran binding protein 11 antibody, Ran-binding protein 11 antibody, RanBP11 antibody, SLRN antibody, Synleurin antibody
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UniProt
- Q9UI26
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途径
- Protein targeting to Nucleus
抗原
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