KPNA6 抗体 (AA 277-536)
Quick Overview for KPNA6 抗体 (AA 277-536) (ABIN7156132)
抗原
See all KPNA6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 277-536
-
交叉反应
- 人, 小鼠
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human Importin subunit alpha-7 protein (277-536AA)
-
亚型
- IgG
-
-
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (Internal Region) antibody
Verified KPNA6 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (AA 101-200) antibodyKPNA6 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (AA 74-123) antibodyKPNA6 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
-
别名
- KPNA6
-
背景
-
Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Aliases: FLJ11249 antibody, IMA7_HUMAN antibody, Importin alpha 7 subunit antibody, Importin alpha S2 antibody, Importin subunit alpha 7 antibody, Importin subunit alpha-7 antibody, IPOA 7 antibody, IPOA7 antibody, Karyopherin alpha 6 antibody, Karyopherin alpha 6 (importin alpha 7) antibody, Karyopherin subunit alpha 6 antibody, Karyopherin subunit alpha-6 antibody, KPNA 6 antibody, KPNA 7 antibody, Kpna6 antibody, KPNA7 antibody, MGC17918 antibody, OTTHUMP00000004532 antibody
-
UniProt
- O60684
-
途径
- Protein targeting to Nucleus
抗原
-
