KPNA1 抗体 (AA 8-538)
Quick Overview for KPNA1 抗体 (AA 8-538) (ABIN7156126)
抗原
See all KPNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-538
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Importin subunit alpha-5 protein (8-538AA)
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亚型
- IgG
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anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-300) antibody
KPNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A4-1B5 unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-538) antibodyKPNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 239-506) antibodyKPNA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 1-539) antibodyKPNA1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2A4-1B5 unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (N-Term) antibodyKPNA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (N-Term) antibodyKPNA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) (AA 74-123) antibodyKPNA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Pig, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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别名
- KPNA1
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背景
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Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
Aliases: IMA5_HUMAN antibody, Importin alpha 1 subunit antibody, Importin alpha 5 antibody, Importin alpha S1 antibody, Importin subunit alpha-5, N-terminally processed antibody, IPO A5 antibody, IPOA 5 antibody, IPOA5 antibody, Karyopherin alpha 1 antibody, Karyopherin alpha 1 subunit antibody, Karyopherin subunit alpha-1 antibody, KPNA 1 antibody, KPNA1 antibody, mSRP 1 antibody, mSRP1 antibody, NPI 1 antibody, NPI-1 antibody, NPI1 antibody, Nucleoprotein interactor 1 antibody, RAG cohort protein 2 antibody, RCH 2 antibody, RCH2 antibody, Recombination activating gene cohort 2 antibody, SRP 1 antibody, SRP1 beta antibody, SRP1-beta antibody
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UniProt
- P52294
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途径
- M Phase, Protein targeting to Nucleus
抗原
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