HORMAD1 抗体 (AA 201-394)
Quick Overview for HORMAD1 抗体 (AA 201-394) (ABIN7155897)
抗原
See all HORMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-394
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human HORMA domain-containing protein 1 protein (201-394AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
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别名
- HORMAD1
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背景
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Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Aliases: HORMAD1 antibody, NOHMA antibody, HORMA domain-containing protein 1 antibody, Cancer/testis antigen 46 antibody, CT46 antibody, Newborn ovary HORMA protein antibody
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UniProt
- Q86X24
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途径
- M Phase
抗原
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