HOMER1 抗体 (AA 1-354) (FITC)
Quick Overview for HOMER1 抗体 (AA 1-354) (FITC) (ABIN7155879)
抗原
See all HOMER1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-354
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Homer protein homolog 1 protein (1-354AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HOMER1 (Homer Homolog 1 (HOMER1))
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别名
- HOMER1
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背景
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Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity).
Aliases: HOME1_HUMAN antibody, Homer antibody, HOMER 1A antibody, HOMER 1B antibody, HOMER 1C antibody, Homer homolog 1 (Drosophila) antibody, homer homolog 1 antibody, Homer protein homolog 1 antibody, homer scaffolding protein 1 antibody, Homer, Drosophila, homolog of, 1 antibody, Homer, neuronal immediate early gene, 1 antibody, Homer-1 antibody, Homer1 antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves 1 antibody
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UniProt
- Q86YM7
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途径
- Skeletal Muscle Fiber Development
抗原
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