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HOMER1 抗体 (AA 1-354)

This anti-HOMER1 antibody is a 兔 多克隆 antibody detecting HOMER1 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7155877
发货至: 中国
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Quick Overview for HOMER1 抗体 (AA 1-354) (ABIN7155877)

抗原

See all HOMER1 抗体
HOMER1 (Homer Homolog 1 (HOMER1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HOMER1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-354

    原理

    HOMER1 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Homer protein homolog 1 protein (1-354AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HOMER1 (Homer Homolog 1 (HOMER1))

    别名

    HOMER1

    背景

    Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity).

    Aliases: HOME1_HUMAN antibody, Homer antibody, HOMER 1A antibody, HOMER 1B antibody, HOMER 1C antibody, Homer homolog 1 (Drosophila) antibody, homer homolog 1 antibody, Homer protein homolog 1 antibody, homer scaffolding protein 1 antibody, Homer, Drosophila, homolog of, 1 antibody, Homer, neuronal immediate early gene, 1 antibody, Homer-1 antibody, Homer1 antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves 1 antibody

    UniProt

    Q86YM7

    途径

    Skeletal Muscle Fiber Development
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