HIPK3 抗体 (AA 841-1130)
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北京 101111
Quick Overview for HIPK3 抗体 (AA 841-1130) (ABIN7155869)
抗原
See all HIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 841-1130
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原理
- HIPK3 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
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亚型
- IgG
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anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) (AA 1127-1156), (C-Term) antibody
HIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3241 unconjugated
anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) antibodyHIPK3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) (Internal Region) antibodyHIPK3 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
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别名
- HIPK3
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背景
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Background: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Aliases: Androgen receptor interacting nuclear protein kinase antibody, Androgen receptor-interacting nuclear protein kinase antibody, ANPK antibody, DYRK6 antibody, Fas interacting serine/threonine protein kinase antibody, Fas-interacting serine/threonine-protein kinase antibody, FIST antibody, FIST3 antibody, Hipk3 antibody, HIPK3_HUMAN antibody, homeodomain interacting protein kinase 3 antibody, Homeodomain-interacting protein kinase 3 antibody, Homolog of protein kinase YAK1 antibody, PKY antibody, RP24 297H17.5 antibody, YAK1 antibody
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UniProt
- Q9H422
抗原
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