MEOX1 抗体 (AA 1-254)
Quick Overview for MEOX1 抗体 (AA 1-254) (ABIN7155798)
抗原
See all MEOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-254
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Homeobox protein MOX-1 protein (1-254AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MEOX1 (Mesenchyme Homeobox 1 (MEOX1))
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别名
- MEOX1
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背景
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Background: Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Aliases: Homeobox protein MOX-1 antibody, MEOX1 antibody, MEOX1_HUMAN antibody, Mesenchyme homeo box 1 antibody, Mesenchyme homeobox 1 antibody, MOX 1 antibody, MOX1 antibody
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UniProt
- P50221
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途径
- Chromatin Binding
抗原
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