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MEIS2 抗体 (AA 377-470)

This anti-MEIS2 antibody is a 兔 多克隆 antibody detecting MEIS2 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7155786
发货至: 中国

Quick Overview for MEIS2 抗体 (AA 377-470) (ABIN7155786)

抗原

See all MEIS2 抗体
MEIS2 (Meis Homeobox 2 (MEIS2))

适用

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宿主

  • 35
  • 5
  • 1

克隆类型

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多克隆

标记

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This MEIS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 377-470

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Homeobox protein Meis2 protein (377-470AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MEIS2 (Meis Homeobox 2 (MEIS2))

    别名

    MEIS2

    背景

    Background: Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, MEIS2 is not involved in complex DNA-binding. Probably in complex with PBX1, is involved in transcriptional regulation by KLF4. Isoform 3 and isoform 4 can bind to a EPHA8 promoter sequence containing the DNA motif 5\\\'-CGGTCA-3\\\', in cooperation with a PBX protein (such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain. May be involved in regulation of myeloid differentiation. Can bind to the DNA sequence 5\\\'-TGACAG-3\\\'in the activator ACT sequence of the D(1A) dopamine receptor (DRD1) promoter and activate DRD1 transcription, isoform 5 cannot activate DRD1 transcription.

    Aliases: Homeobox protein Meis2 antibody, HsT18361 antibody, Meis (mouse) homolog 2 antibody, Meis homeobox 2 antibody, Meis homolog 2 antibody, Meis1 myeloid ecotropic viral integration site 1 homolog 2 (mouse) antibody, Meis1 myeloid ecotropic viral integration site 1 homolog 2 antibody, Meis1 related gene 1 antibody, Meis1 related protein 1 antibody, Meis1-related protein 1 antibody, MEIS2 antibody, MEIS2_HUMAN antibody, MGC2820 antibody, MRG1 antibody, TALE homeobox protein Meis2 antibody

    UniProt

    O14770
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