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PAK6 抗体 (pSer165) (HRP)

This anti-PAK6 antibody is a 兔 多克隆 antibody detecting PAK6 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN711320
发货至: 中国

Quick Overview for PAK6 抗体 (pSer165) (HRP) (ABIN711320)

抗原

See all PAK6 抗体
PAK6 (P21-Activated Kinase 6 (PAK6))

适用

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人, 小鼠

宿主

  • 78

克隆类型

  • 77
多克隆

标记

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This PAK6 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
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    pSer165

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PAK6 around the phosphorylation site of Ser165

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PAK6 (P21-Activated Kinase 6 (PAK6))

    别名

    PAK6

    背景

    Synonyms: PAK6phospho S165, CDKN1A activated kinase 6, p21 activated protein kinase 6, p21 protein Cdc42/Rac-activated kinase 6, p21CDKN1A activated kinase 6, p21-ACTIVATED KINASE 6, p21activated kinase 6, PAK 5, PAK 6, PAK5, Serine threonine protein kinase PAK 6, Serine/threonine protein kinase PAK 6, Serine/threonine protein kinase PAK6.

    Background: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

    基因ID

    56924
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