PAK6 抗体 (pSer165) (Cy7)
Quick Overview for PAK6 抗体 (pSer165) (Cy7) (ABIN711317)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer165
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human PAK6 around the phosphorylation site of Ser165
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- PAK6 (P21-Activated Kinase 6 (PAK6))
-
别名
- PAK6
-
背景
-
Synonyms: PAK6phospho S165, CDKN1A activated kinase 6, p21 activated protein kinase 6, p21 protein Cdc42/Rac-activated kinase 6, p21CDKN1A activated kinase 6, p21-ACTIVATED KINASE 6, p21activated kinase 6, PAK 5, PAK 6, PAK5, Serine threonine protein kinase PAK 6, Serine/threonine protein kinase PAK 6, Serine/threonine protein kinase PAK6.
Background: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
-
基因ID
- 56924
抗原
-