H2AFB1 抗体 (AA 1-115) (Biotin)
Quick Overview for H2AFB1 抗体 (AA 1-115) (Biotin) (ABIN7155374)
抗原
See all H2AFB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-115
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
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别名
- H2AFB1
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背景
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Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.
Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody
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UniProt
- P0C5Y9
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途径
- Telomere Maintenance
抗原
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