SAP18 抗体 (AA 2-153)
Quick Overview for SAP18 抗体 (AA 2-153) (ABIN7155341)
抗原
See all SAP18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-153
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Histone deacetylase complex subunit SAP18 protein (2-153AA)
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亚型
- IgG
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anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 21-172) antibody
SAP18 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 30-79) antibodySAP18 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (N-Term) antibodySAP18 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
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别名
- SAP18
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背景
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Background: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes), specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S), the activity is different from the established EJC assembly and function.
Aliases: 18 kDa Sin3-associated polypeptide antibody, 2HOR0202 antibody, Cell growth-inhibiting gene 38 protein antibody, Histone deacetylase complex subunit SAP18 antibody, SAP18 antibody, SAP18_HUMAN antibody, Sin3-associated polypeptide p18 antibody
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UniProt
- O00422
抗原
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