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HDAC4 抗体 (AA 1-227)

This anti-HDAC4 antibody is a 兔 多克隆 antibody detecting HDAC4 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7155314
发货至: 中国

Quick Overview for HDAC4 抗体 (AA 1-227) (ABIN7155314)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

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宿主

  • 109
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克隆类型

  • 106
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多克隆

标记

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This HDAC4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1-227

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Histone deacetylase 4 protein (1-227AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    背景

    Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at \\\'Lys-77\\\' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).

    Aliases: AHO3 antibody, BDMR antibody, EC 3.5.1.98 antibody, HA6116 antibody, HD 4 antibody, HD4 antibody, HDAC 4 antibody, HDAC A antibody, HDAC4 antibody, HDAC4_HUMAN antibody, HDACA antibody, Histone deacetylase 4 antibody, Histone Deacetylase A antibody, KIAA0288 antibody

    UniProt

    P56524

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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