HARS1/Jo-1 抗体 (AA 1-180)
Quick Overview for HARS1/Jo-1 抗体 (AA 1-180) (ABIN7155257)
抗原
See all HARS1/Jo-1 (HARS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-180
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Histidine--tRNA ligase, cytoplasmic protein (1-180AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
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别名
- HARS
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背景
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Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.
Aliases: cytoplasmic antibody, EC 6.1.1.21 antibody, FLJ20491 antibody, HARS antibody, HisRS antibody, Histidine tRNA ligase, cytoplasmic antibody, histidine translase antibody, Histidine tRNA ligase antibody, Histidine--tRNA ligase antibody, Histidyl tRNA synthetase antibody, Histidyl-tRNA synthetase antibody, HRS antibody, Human histidyl tRNA synthetase homolog (HO3) mRNA complete cds antibody, SYHC_HUMAN antibody, USH3B antibody
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UniProt
- P12081
抗原
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