PDE9A 抗体 (AA 426-533)
Quick Overview for PDE9A 抗体 (AA 426-533) (ABIN7155179)
抗原
See all PDE9A 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 426-533
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                                            交叉反应
- 人
- 
                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human High affinity cGMP-specific 3\\\',5\\\'-cyclic phosphodiesterase 9A protein (426-533AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - PDE9A (phosphodiesterase 9A (PDE9A))
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                                            别名
- PDE9A
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                                            背景
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                        Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity). Aliases: 5''-cyclic phosphodiesterase 9A antibody, cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody, FLJ90181 antibody, High affinity cGMP-specific 3'' antibody, High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody, HSPDE9A2 antibody, OTTHUMP00000109399 antibody, PDE 9A antibody, Pde9a antibody, PDE9A_HUMAN antibody, Phosphodiesterase 9A antibody, phosphodiesterase PDE9A21 antibody 
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                                            UniProt
- O76083
 抗原
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