PDE9A 抗体 (AA 426-533)
Quick Overview for PDE9A 抗体 (AA 426-533) (ABIN7155179)
抗原
See all PDE9A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 426-533
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human High affinity cGMP-specific 3\\\',5\\\'-cyclic phosphodiesterase 9A protein (426-533AA)
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亚型
- IgG
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anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibody
PDE9A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 434-533) antibodyPDE9A 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibodyPDE9A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 136-185) antibodyPDE9A 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PDE9A (phosphodiesterase 9A (PDE9A))
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别名
- PDE9A
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背景
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Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).
Aliases: 5''-cyclic phosphodiesterase 9A antibody, cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody, FLJ90181 antibody, High affinity cGMP-specific 3'' antibody, High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody, HSPDE9A2 antibody, OTTHUMP00000109399 antibody, PDE 9A antibody, Pde9a antibody, PDE9A_HUMAN antibody, Phosphodiesterase 9A antibody, phosphodiesterase PDE9A21 antibody
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UniProt
- O76083
抗原
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