PDE8A 抗体 (AA 596-829) (Biotin)
Quick Overview for PDE8A 抗体 (AA 596-829) (Biotin) (ABIN7155165)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 596-829
- 
                                            交叉反应
- 人
- 
                                            纯化方法
- Antigen Affinity Purified
- 
                                            免疫原
- Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3\',5\'-cyclic phosphodiesterase 8A protein (596-829AA)
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- Optimal working dilution should be determined by the investigator.
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            缓冲液
- 
                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C,-80 °C
- 
                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
- 
                                            
- 
    - PDE8A (phosphodiesterase 8A (PDE8A))
- 
                                            别名
- PDE8A
- 
                                            背景
- 
                        Background: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 \'Ser-259\' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299). Aliases: 5''-cyclic phosphodiesterase 8A antibody, cAMP specific cyclic nucleotide phosphodiesterase 8A antibody, FLJ16150 antibody, High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody, High affinity cAMP-specific and IBMX-insensitive 3'' antibody, HsT19550 antibody, PDE 8A antibody, PDE8A antibody, PDE8A_HUMAN antibody, Phosphodiesterase 8A antibody, Phosphodiesterase8A antibody, Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody 
- 
                                            UniProt
- O60658
- 
                                            途径
- cAMP Metabolic Process
 抗原
- 
                    
 
                                     
                                     
                                    