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GRB7 抗体 (AA 233-532)

The 兔 多克隆 anti-GRB7 antibody (ABIN7154506) specifically detects GRB7 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7154506
发货至: 中国
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Quick Overview for GRB7 抗体 (AA 233-532) (ABIN7154506)

抗原

See all GRB7 抗体
GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))

适用

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宿主

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克隆类型

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多克隆

标记

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This GRB7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 233-532

    原理

    GRB7 Antibody

    交叉反应

    大鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))

    别名

    GRB7

    背景

    Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5\\\'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

    Aliases: B47 antibody, Epidermal growth factor receptor GRB 7 antibody, Epidermal growth factor receptor GRB-7 antibody, GRB7 adapter protein antibody, GRB7 antibody, GRB7_HUMAN antibody, Growth factor receptor bound protein 7 antibody, Growth factor receptor-bound protein 7 antibody, OTTHUMP00000164349 antibody, OTTHUMP00000164350 antibody, OTTHUMP00000164351 antibody, OTTHUMP00000164352 antibody

    UniProt

    Q14451

    途径

    EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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