GRB14 抗体 (AA 294-397) (FITC)
Quick Overview for GRB14 抗体 (AA 294-397) (FITC) (ABIN7154500)
抗原
See all GRB14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 294-397
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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别名
- GRB14
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背景
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Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody
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UniProt
- Q14449
抗原
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