GLRB 抗体 (AA 355-472)
Quick Overview for GLRB 抗体 (AA 355-472) (ABIN7154190)
抗原
See all GLRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 355-472
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Glycine receptor subunit beta protein (355-472AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IF:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GLRB (Glycine Receptor, beta (GLRB))
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别名
- GLRB
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背景
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Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).
Aliases: GLRBGlycine receptor subunit beta antibody, Glycine receptor 58 kDa subunit antibody
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UniProt
- P48167
抗原
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