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GLRB 抗体 (AA 355-472)

This 兔 多克隆 anti-GLRB antibody specifically detects GLRB in ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7154190
发货至: 中国
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Quick Overview for GLRB 抗体 (AA 355-472) (ABIN7154190)

抗原

See all GLRB 抗体
GLRB (Glycine Receptor, beta (GLRB))

适用

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宿主

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克隆类型

  • 40
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多克隆

标记

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This GLRB antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 355-472

    原理

    GLRB Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Glycine receptor subunit beta protein (355-472AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GLRB (Glycine Receptor, beta (GLRB))

    别名

    GLRB

    背景

    Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

    Aliases: GLRBGlycine receptor subunit beta antibody, Glycine receptor 58 kDa subunit antibody

    UniProt

    P48167
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