GRIA4 抗体 (AA 733-883)
Quick Overview for GRIA4 抗体 (AA 733-883) (ABIN7153965)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 733-883
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Glutamate receptor 4 protein (733-883AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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别名
- GRIA4
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背景
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Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Aliases: AMPA 4 antibody, AMPA selective glutamate receptor 4 antibody, AMPA-selective glutamate receptor 4 antibody, AMPA4 antibody, GluA 4 antibody, GluA4 antibody, GluR 4 antibody, GluR D antibody, GluR-4 antibody, GluR-D antibody, GluR4 antibody, GLUR4C antibody, GLURD antibody, Glutamate receptor 4 antibody, Glutamate receptor ionotrophic AMPA 4 antibody, Glutamate receptor ionotropic antibody, GRIA 4 antibody, Gria4 antibody, GRIA4_HUMAN antibody, Ionotropic Glutamate receptor 4 antibody
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UniProt
- P48058
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途径
- PI3K-Akt Signaling
抗原
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