GEMIN6 抗体 (AA 1-167)
Quick Overview for GEMIN6 抗体 (AA 1-167) (ABIN7153761)
抗原
See all GEMIN6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-167
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Gem-associated protein 6 protein (1-167AA)
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6) (AA 1-167) antibody
GEMIN6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6) (AA 1-167) antibodyGEMIN6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6) (AA 62-111) antibodyGEMIN6 适用: 人, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6) (AA 1-167) antibodyGEMIN6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
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别名
- GEMIN6
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背景
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Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Aliases: FLJ23459 antibody, Gem (nuclear organelle) associated protein 6 antibody, Gem-associated protein 6 antibody, GEMI6 antibody, GEMI6_HUMAN antibody, Gemin 6 antibody, Gemin-6 antibody, Gemin6 antibody, SIP2 antibody
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UniProt
- Q8WXD5
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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