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SIP1 抗体 (AA 1-280)

This anti-SIP1 antibody is a 兔 多克隆 antibody detecting SIP1 in WB, ELISA, IF 和 IP. Suitable for 人.
产品编号 ABIN7153753
发货至: 中国

Quick Overview for SIP1 抗体 (AA 1-280) (ABIN7153753)

抗原

See all SIP1 (GEMIN2) 抗体
SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

适用

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宿主

  • 40
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克隆类型

  • 40
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多克隆

标记

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This SIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

    • 6
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    AA 1-280

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Gem-associated protein 2 protein (1-280AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200, IP:1:200-1:2000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

    别名

    GEMIN2

    背景

    Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Aliases: Component of gems 2 antibody, Gem (nuclear organelle) associated protein 2 antibody, Gem associated protein 2 antibody, GEMI2_HUMAN antibody, Gemin-2 antibody, gemin2 antibody, SIP 1 antibody, SIP-1 antibody, SIP1 antibody, SIP1 delta antibody, SIP1-delta antibody, SMN interacting protein 1 antibody, SMN interacting protein 1 delta antibody, SMN-interacting protein 1 antibody, Survival interacting protein 1 antibody, Survival of motor neuron protein interacting protein 1 antibody, Survival of motor neuron protein-interacting protein 1 antibody

    UniProt

    O14893

    途径

    Ribonucleoprotein Complex Subunit Organization, Tube Formation
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