WDR24 抗体 (AA 1-298) (HRP)
Quick Overview for WDR24 抗体 (AA 1-298) (HRP) (ABIN7153708)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-298
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human GATOR complex protein WDR24 protein (1-298AA)
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亚型
- IgG
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anti-WD Repeat Domain 24 (WDR24) (AA 1-298) antibody
WDR24 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WDR24 (WD Repeat Domain 24 (WDR24))
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别名
- WDR24
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背景
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody
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UniProt
- Q96S15
抗原
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