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WDR24 抗体 (AA 1-298) (FITC)

WDR24 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7381319
发货至: 中国
  • 抗原 See all WDR24 products
    WDR24 (WD Repeat Domain 24 (WDR24))
    抗原表位
    • 4
    • 1
    AA 1-298
    适用
    • 8
    • 1
    宿主
    • 8
    克隆类型
    • 8
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    This WDR24 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human GATOR complex protein WDR24 protein (1-298AA)
    亚型
    IgG
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WDR24 (WD Repeat Domain 24 (WDR24))
    别名
    WDR24 (WDR24 产品)
    别名
    C16orf21 antibody, JFP7 antibody, BC037651 antibody, wu:fd05f12 antibody, zgc:55946 antibody, WD repeat domain 24 antibody, WD repeat domain 24 L homeolog antibody, WDR24 antibody, Wdr24 antibody, wdr24 antibody, wdr24.L antibody
    背景

    Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).

    Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody

    UniProt
    Q96S15
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