Gasdermin A 抗体 (AA 64-172)
Quick Overview for Gasdermin A 抗体 (AA 64-172) (ABIN7153647)
抗原
See all Gasdermin A (GSDMA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 64-172
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Gasdermin-A protein (64-172AA)
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亚型
- IgG
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anti-Gasdermin A (GSDMA) (AA 21-120) antibody
GSDMA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin A (GSDMA) (AA 223-272) antibodyGSDMA 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin A (GSDMA) (AA 66-94), (N-Term) antibodyGSDMA 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24996 unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Gasdermin A (GSDMA)
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别名
- GSDMA
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背景
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Background: May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
Aliases: GSDMA antibody, GSDM antibody, GSDM1 antibody, FKSG9Gasdermin-A antibody, Gasdermin-1 antibody
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UniProt
- Q96QA5
抗原
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