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GPR161 抗体 (AA 1-28) (HRP)

This anti-GPR161 antibody is a 兔 多克隆 antibody detecting GPR161 in ELISA. Suitable for 人.
产品编号 ABIN7153330
发货至: 中国

Quick Overview for GPR161 抗体 (AA 1-28) (HRP) (ABIN7153330)

抗原

See all GPR161 抗体
GPR161 (G Protein-Coupled Receptor 161 (GPR161))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPR161 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 1-28

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GPR161 (G Protein-Coupled Receptor 161 (GPR161))

    别名

    GPR161

    背景

    Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

    Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody

    UniProt

    Q8N6U8

    途径

    cAMP Metabolic Process
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