FOXL2 抗体 (AA 116-216) (HRP)
Quick Overview for FOXL2 抗体 (AA 116-216) (HRP) (ABIN7153065)
抗原
See all FOXL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 116-216
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Forkhead box protein L2 protein (116-216AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FOXL2 (Forkhead Box L2 (FOXL2))
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别名
- FOXL2
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背景
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Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Aliases: Blepharophimosis antibody, Blepharophimosis epicanthus inversus and ptosis 1 antibody, Blepharophimosis epicanthus inversus and ptosis antibody, BPES 1 antibody, BPES antibody, BPES1 antibody, Epicanthus inversus and ptosis 1 antibody, Forkhead box L2 antibody, Forkhead box protein L2 antibody, Forkhead transcription factor FOXL2 antibody, FOX L2 antibody, FOXL 2 antibody, FOXL2 antibody, FOXL2_HUMAN antibody, PFRK antibody, PINTO antibody, PITUITARY FORKHEAD FACTOR antibody, POF 3 antibody, POF3 antibody
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UniProt
- P58012
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途径
- Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
抗原
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