Filamin A 抗体 (AA 1234-1462) (Biotin)
Quick Overview for Filamin A 抗体 (AA 1234-1462) (Biotin) (ABIN7152945)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1234-1462
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Filamin-A protein (1234-1462AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- FLNA
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背景
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Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).
Aliases: ABP 280 antibody, ABP-280 antibody, Actin-binding protein 280 antibody, Alpha filamin antibody, Alpha-filamin antibody, APBX antibody, CSBS antibody, CVD1 antibody, Endothelial actin binding protein antibody, Endothelial actin-binding protein antibody, Filamin 1 antibody, Filamin A alpha antibody, Filamin A antibody, Filamin-1 antibody, Filamin-A antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FLNA antibody, FLNA_HUMAN antibody, FMD antibody, MNS antibody, NHBP antibody, Non muscle filamin antibody, Non-muscle filamin antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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